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Quinidine and melittin both decrease the fluidity of liver plasma membranes and both inhibit hormone-stimulated adenylate cyclase activity

✍ Scribed by Lindsey Needham; Nicholas J.F. Dodd; Miles D. Houslay

Book ID
115728103
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
492 KB
Volume
899
Category
Article
ISSN
0005-2736

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✍ Gordon, Larry M. ;Dipple, Irene ;Sauerheber, Richard D. ;Esgate, Judy A. ;Housla πŸ“‚ Article πŸ“… 1980 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 641 KB

## Abstract The cationic local anaesthetics carbocaine and unpercaine were found to increase the fluoride‐stimulated adenylate cyclase up to a maximum level; above this maximum level further increases in drug concentration inhibited the enzyme. At concentrations where this activity was stimulated,