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Questions and Answers : Session VII: The NMDA Receptor as a Target for Neurotoxicity and Neuroprotection


Book ID
111398377
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
52 KB
Volume
1053
Category
Article
ISSN
0890-6564

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The NMDA receptor antagonist memantine a
โœ Wojciech Danysz; Chris G. Parsons ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 407 KB ๐Ÿ‘ 1 views

There is increasing evidence for the involvement of glutamate-mediated neurotoxicity in the pathogenesis of Alzheimer's disease (AD). We suggest that glutamate receptors of the N-methyl-D-aspartate (NMDA) type are overactivated in a tonic rather than a phasic manner in this disorder. This continuous