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Quercetin induced tissue-type plasminogen activator expression is mediated through Sp1 and p38 mitogen-activated protein kinase in human endothelial cells

✍ Scribed by W. PAN; M. J. CHANG; F. M. BOOYSE; H. E. GRENETT; K. M. BRADLEY; P. E. WOLKOWICZ; Q. SHANG; E. M. TABENGWA


Book ID
109152535
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
490 KB
Volume
6
Category
Article
ISSN
1538-7933

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Pyrrolidine dithiocarbamate (PDTC), a metal chelating compound, is known to induce cell death in vascular smooth muscle cells (VSMC). However, the molecular mechanism for PDTC-induced VSMC death is not well understood. Addition of PDTC reduced cell growth and DNA synthesis on VSMC in low density con