During diabetes, structural and functional changes in the alimentary tract are known to take place resulting in increased absorption of intestinal glucose and alterations in the activities of brush border disaccharidases. Similar observations are also reported in the renal cortex. In the present inv
Quercetin alleviates activities of intestinal and renal disaccharidases in streptozotocin-induced diabetic rats
β Scribed by Rashmi Ramachandra; Ajaya K. Shetty; Paramahans V. Salimath
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 427 KB
- Volume
- 49
- Category
- Article
- ISSN
- 1613-4125
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β¦ Synopsis
Specific activities of both intestinal and renal dissacharidases, such as sucrase, maltase, and lactase, were altered in diabetic rats. Our study was focused to evaluate the effect of feeding quercetin -a bioflavanoid on intestinal and renal dissacharidases in streptozotocin-induced diabetic rats. The rats were fed with 0.1% quercetin in diet. A reduction in intestinal maltase and sucrase, activities in quercetin-fed diabetic rats was observed in contrast to the increased activities in the starch-fed diabetic rats. A significant amelioration in renal dissacharidase activities in quercetin-fed diabetic rats was observed when compared to decreased activity in starch-fed diabetic rats.
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