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Quercetin, a bioflavonoid, reverses development of tolerance and dependence to morphine

✍ Scribed by Amanpreet Singh; Pattipati S. Naidu; Shrinivas K. Kulkarni


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
99 KB
Volume
57
Category
Article
ISSN
0272-4391

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Comparison of tolerance development and
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The tolerance-development capacities of beta-endorphin, [D-Met2, Pro5]-enkephalinamide, and morphine were compared in rats, and the dependence capacity of morphine was compared with that of the enkephalin analogue in mice. Tolerance to the analgesic effect, as measured by the tail-flick test, develo