To clarify the virological differences in patients with chronic hepatitis C virus (HCV) infection with and without liver damage, we assessed HCV markers in 306 patients from a rural area of Japan. Genotypes of HCV RNA were determined by polymerase chain reaction, and levels of RNA were determined by
Quasispecies of hepatitis C virus in serum and in three different parts of the liver of patients with chronic hepatitis
โ Scribed by Akito Sakai; Shuichi Kaneko; Masao Honda; Eiki Matsushita; Kenichi Kobayashi
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 185 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Evolution of hepatitis C quasispecies may be one mechanism by which fibrosing cholestatic hepatitis develops after liver transplantation. In this study, we compared changes in quasispecies complexity and/or divergence in (1) hepatitis C-infected immunosuppressed transplant recipients and in immunoco
The quasispecies nature of hepatitis C virus (HCV) in patients with mixed HCV subtype infection was compared with that in patients with single HCV subtype infection. The number of HCV quasispecies was compared between 35 patients with mixed HCV subtype infection and 83 patients with single subtype i
## Abstract Although occult hepatitis B virus (HBV) infection (HBVโDNA in serum in the absence of hepatitis B surface antigen [HBsAg]) is common in chronic hepatitis C, its characteristics are not well known. In this work, the presence of HBVโDNA (by polymerase chain reaction; PCR) and its distribu
## Abstract Hepatitis B virus (HBV) DNA may persist in the liver in the absence of serum HBVโDNA after a selfโlimited acute hepatitis B. This may also occur in patients with chronic hepatitis C virus (HCV) infection but its prevalence and its impact on liver histology is unknown. HBVโDNA was tested
Hepatitis C virus RNA as detected by reverse transcription and nested polymerase chain reaction was monitored in 16 patients with chronic hepatitis C treated with interferon. Hepatitis C virus R N A became undetectable after 4 to 8 wk of interferon administration in 13 of the 16 patients. During 6 m