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Quasispecies Heterogeneity and Constraints on the Evolution of the 5′ Noncoding Region of Hepatitis C Virus (HCV): Relationship with HCV Resistance to Interferon-α Therapy

✍ Scribed by Muriel Soler; Muriel Pellerin; Cécile E. Malnou; Daniel Dhumeaux; Katherine M. Kean; Jean-Michel Pawlotsky


Book ID
112274100
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
205 KB
Volume
298
Category
Article
ISSN
0042-6822

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## Abstract The use of two new assays was evaluated for predicting the response to interferon (IFN) therapy in patients with chronic hepatitis C. The genotype of hepatitis C virus (HCV) was establishe by an enzyme‐linked immunosorbent assay based on genotype‐specific recombinant peptides of the NS4