Quantum-Dynamical Picture of a Multistep Enzymatic Process: Reaction Catalyzed by Phospholipase A2
✍ Scribed by Bała, P.; Grochowski, P.; Nowiński, K.; Lesyng, B.; McCammon, J.A.
- Book ID
- 118513565
- Publisher
- Biophysical Society
- Year
- 2000
- Tongue
- English
- Weight
- 619 KB
- Volume
- 79
- Category
- Article
- ISSN
- 0006-3495
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## Abstract __The enzymatic hydrolysis of an L‐dipalmitoylphosphatidylcholine (L‐DPPC) monolayer at the air/water interface, catalyzed by phospholipase A__~__2__~ __(PLA__~__2__~__), serves as a model for biospecific interfacial reactions. The cleavage of L‐DPPC was investigated by Brewster angle m
؊1 , respectively. The results for the residual dipolar interactions were verified by repeating the above measurements at a temperature of 1.5°C, where the spectra of the H 2 O molecules were well resolved, so that the 1 H-1 H dipolar interaction could be determined directly from the observed splitt