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Quantitative Study of Competitive Binding of Drugs to Protein by Microdialysis/High-Performance Liquid Chromatography

✍ Scribed by Wang, Hailin; Zou, Hanfa; Zhang, Yukui

Book ID
126426726
Publisher
American Chemical Society
Year
1998
Tongue
English
Weight
52 KB
Volume
70
Category
Article
ISSN
0003-2700

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✍ Hamlin Wang; Hanfa Zou; Yukui Zhang πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 72 KB πŸ‘ 2 views

A simple and fast method for the determination of the multi-site binding of fenoprofen (FP) to human serum albumin (HSA) has been developed by utilizing microdialysis sampling techniques combined with high performance liquid chromatography (HPLC). The drug and protein were mixed in different molar r