Variation in the level of fetal hemoglobin (HbF) accounts for much of the clinical heterogeneity observed in patients with sickle cell disease (SCD). The HbF level has emerged as an important prognostic factor in both sickle cell pain and mortality, and a % HbF of 10-20% has been suggested as a thre
β¦ LIBER β¦
Quantitative Studies of Ferritinlike Iron in Erythrocytes of Thalassemia, Sickle-Cell Anemia, and Hemoglobin Hammersmith with Mossbauer Spectroscopy
β Scribed by E. R. Bauminger, S. G. Cohen, S. Ofer and E. A. Rachmilewitz
- Book ID
- 123655647
- Publisher
- National Academy of Sciences
- Year
- 1979
- Tongue
- English
- Weight
- 828 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/69187
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## Abstract A natural history study was conducted in 142 Thalassemic (Thal), 199 transfused Sickle Cell Disease (TxβSCD, __n__ = 199), and 64 nonβTxβSCD subjects to describe the frequency of ironβrelated morbidity and mortality. Subjects recruited from 31 centers in the US, Canada or the UK were si