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Quantitative structure–activity relationships (QSARs) for the prediction of skin permeation of exogenous chemicals

✍ Scribed by Hiren Patel; Wil ten Berge; Mark T.D. Cronin

Book ID
117249125
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
133 KB
Volume
48
Category
Article
ISSN
0045-6535

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Studies were previously conducted in our laboratory on the influence of n-alkanols, 1-alkyl-2-pyrrolidones, N,N-dimethlyalkanamides, and 1,2-alkanediols as skin permeation enhancers on the transport of a model permeant, corticosterone (CS). The experiments were conducted with hairless mouse skin (HM