𝔖 Bobbio Scriptorium
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Quantitative Structure−Activity Relationship Model for Prediction of Genotoxic Potential for Quinolone Antibacterials

✍ Scribed by Hu, Jianying; Wang, Wanfeng; Zhu, Zhou; Chang, Hong; Pan, Feng; Lin, Binle


Book ID
126870521
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
271 KB
Volume
41
Category
Article
ISSN
0013-936X

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## Abstract A simple and reproducible quantitative retention–activity relationship (QRAR) model utilizing biopartitioning micellar chromatography was developed for the biological parameter estimation of drugs. The correlation between retention factors of quinolones obtained in physiological conditi