Quantitative structure-fungicidal activity relationships of N -(4-difluoromethoxybenzyl)pyrimidin-4-amines against wheat and barley fungi
✍ Scribed by Yamanaka, Yoshinori; Moritomo, Masaru; Fujii, Katsutoshi; Tanaka, Toshinobu; Fukuda, Yasuhisa; Nishimura, Keiichiro
- Book ID
- 101215715
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 105 KB
- Volume
- 55
- Category
- Article
- ISSN
- 1526-498X
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✦ Synopsis
A set of N-(4-di¯uoromethoxybenzyl)pyrimidinamines with various substituents at the 4and 5-positions of the pyrimidine ring and at the benzyl position were prepared, and their fungicidal activities against wheat brown rust, Puccinia recondita, and barley powdery mildew, Erisiphe graminis, were measured. Variations in each of these activities were quantitatively analysed by the use of physicochemical substituent parameters and a regression analysis. Each of these activities was parabolically correlated with the steric bulkiness of the pyrimidine substituents and with the bulkiness or the hydrophobicity of the benzylic substituents.