✍ Scribed by P. Tömpe; Gy. Clementis; I. Petneházy; Zs.M. Jászay; L. Tőke
No coin nor oath required. For personal study only.
The half-wave potential (E,,,) of 26 substituted cu,P-unsaturated ketones in non-aqueous acetonitrile were used in Hammett type quantitative structure-activity relationship (QSAR) analysis. A linear relationship between E,,, and the electronic substituent constant, a, and reaction constant pR was revealed for 17 substituted chalcones. Linear regression equations were calculated using only the sum of cXx,para + a,,,,,, of all substituents. It was found that the production of the substituted 1,2-oxaphosphol-4-en in the redox reaction of the CY, P-unsaturated ketones and trialkyl phosphite can be predicted from the E 1/Z values of the a,P_unsaturated ketones measured in nonprotic solvent. The E,,, values also give a linear correlation with the conversions of the starting ketones.
📜 SIMILAR VOLUMES
## 2-Cycloen-1 -ones / Caroate The synthesis of epoxides 3ar is achieved in excellent yields by reaction of the a,P-unsaturated ketones l a -c , 4,4'-disubstituted (E)-chalcones 1 d -0 , and 2'-hydroxy-4-substituted (E)chalcones l p -r with isolated dimethyldioxirane (2a) (as ac-etone solution) an