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Quantitative Structure-Activity Relationships of Sweet Isovanillyl Derivatives

โœ Scribed by Bassoli, Angela ;Drew, Michael G.B. ;Hattotuwagama, Channa K. ;Merlini, Lucio ;Morini, Gabriella ;Wilden, Gareth R.H.


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
309 KB
Volume
20
Category
Article
ISSN
1611-020X

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A series of substituted aryltriazolinones, known to inhibit protoporphyrinogen oxidase, were prepared and their structureรˆactivity requirements at positions 4 and 5 of the aromatic ring investigated. A QSAR equation obtained for substituents at the 5 position identiรed the hydrophobicity term n and