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Quantitative structure-activity relationships of competitive inhibitors of phosphoenolpyruvate carboxylase

✍ Scribed by Ricardo L. Mancera; Ariadne G. Gómez; Alejandro Pisanty


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
743 KB
Volume
3
Category
Article
ISSN
0968-0896

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## Abstract Structure‐based quantitative structure‐activity relationship (QSAR) studies on a series of checkpoint kinase 1 (Chk1) inhibitors were performed to find the key structural features responsible for their inhibitory activity. Molecular docking was employed to explore the binding mode of al