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Quantitative reexamination of structure-activity relations in the .DELTA.6-6-substituted progesterone series

✍ Scribed by Wolff, Manfred E.; Hansch, Corwin


Book ID
126154299
Publisher
American Chemical Society
Year
1974
Tongue
English
Weight
411 KB
Volume
17
Category
Article
ISSN
0022-2623

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## Abstract Several morphinanone agonists differently substituted at C(3), C(4), C(5) and C (14) and antagonists of the 4‐hydroxy and 3, 4‐dimethoxy series were prepared by conventional chemistry. It was demonstrated that the oxygenation pattern in the bay‐area, encompassing C(3) and C(4), is impor