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Quantitative Reconstitution of Mitotic CDK1 Activation in Somatic Cell Extracts

โœ Scribed by Richard W. Deibler; Marc W. Kirschner

Book ID
116754852
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
945 KB
Volume
37
Category
Article
ISSN
1097-2765

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## Abstract Skeletal development and osteoblast maturation require the phenotype promoting activity of the transcription factor RUNX2, which controls both cell growth and differentiation in osteoblasts. We have recently shown that in actively proliferating cells RUNX2 regulates the expression of sp