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Quantitative proteomic analysis of age-related changes in human cerebrospinal fluid

✍ Scribed by Jing Zhang; David R. Goodlett; Elaine R. Peskind; Joseph F. Quinn; Yong Zhou; Qin Wang; Catherine Pan; Eugene Yi; Jimmy Eng; Ruedi H. Aebersold; Thomas J. Montine

Book ID: 116780500
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 257 KB
Volume: 26
Category: Article
ISSN: 0197-4580
DOI: 10.1016/j.neurobiolaging.2004.03.012

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There is an urgent need for novel biomarkers that can be used to improve the diagnosis, predict the disease progression, improve our understanding of the pathology or serve as therapeutic targets for neurodegenerative diseases. Cerebrospinal fluid (CSF) is in direct contact with the CNS and reflects