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Quantitative profiling of polar primary metabolites using hydrophilic interaction ultrahigh performance liquid chromatography–tandem mass spectrometry

✍ Scribed by Gika, Helen G.; Theodoridis, Georgios A.; Vrhovsek, Urska; Mattivi, Fulvio


Book ID
120316813
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
497 KB
Volume
1259
Category
Article
ISSN
1873-3778

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## Abstract Hydrophilic interaction LC with MS/MS (HILIC‐MS/MS) was described as a rapid, sensitive, and selective method for the quantification of doxazosin in human plasma. Doxazosin and cisapride (internal standard) were extracted from human plasma with ethyl acetate at alkaline pH and analyzed