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Quantitative morphological aspects of granulocytic differentiation induced in HL-60 cells by dimethylsulfoxide and retinoic acid

✍ Scribed by Jean Dufer; Daniel Biakou; Philippe Joly; Hervé Benoist; Yves Carpentier; Andrée Desplaces

Book ID
113239124
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
585 KB
Volume
13
Category
Article
ISSN
0145-2126

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## Abstract During differentiation of human leukemic HL60 cells into granulocytes, sustained increases in intracellular pH and Na^+^/H^+^ antiporter activity have been observed. In the present study we report that retinoic acid (RA)‐induced granulocytic differentiation of HL60 cells causes an ∼18‐f