Quantitative measurement of Human Papillomavirus type 16 L1/L2 DNA methylation correlates with cervical disease grade
β Scribed by Bryant, Dean; Tristram, Amanda; Liloglou, Triantafillos; Hibbitts, Samantha; Fiander, Alison; Powell, Ned
- Book ID
- 121392545
- Publisher
- Elsevier Science
- Year
- 2014
- Tongue
- English
- Weight
- 624 KB
- Volume
- 59
- Category
- Article
- ISSN
- 1386-6532
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## Abstract Human papillomavirusβ16 DNA replicates in productive infections in circular form, but is found in most carcinomas integrated into the host cell DNA. Because this transition is essential for carcinogenesis, detailed research is desirable and may help to triage patients with abnormal Pap
## Abstract Specific types of human papillomavirus (HPV) are known to play a causal role in the development of cervical cancer, with human papillomavirus type 16 (HPVβ16) identified as the predominant type. Despite this, little is known about cervical immune responses to this pathogen. The aim of t