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Quantitative label-free proteomics for discovery of biomarkers in cerebrospinal fluid: Assessment of technical and inter-individual variation

✍ Scribed by Perrin, Richard; Payton, Jacqueline; Malone, James; Gilmore, Petra; Davis, Alan; Xiong, Chengjie; Fagan, Anne; Townsend, R. Reid; Holtzman, David

Book ID
122415047
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
49 KB
Volume
9
Category
Article
ISSN
1552-5260

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There is an urgent need for novel biomarkers that can be used to improve the diagnosis, predict the disease progression, improve our understanding of the pathology or serve as therapeutic targets for neurodegenerative diseases. Cerebrospinal fluid (CSF) is in direct contact with the CNS and reflects