𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Quantitative interpretation of magnetization transfer

✍ Scribed by R. Mark Henkelman; Xuemei Huang; Qing-San Xiang; G. J. Stanisz; Scott D. Swanson; Michael J. Bronskill

Book ID
102954695
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
964 KB
Volume
29
Category
Article
ISSN
0740-3194

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Magnetization transfer contrast (MTC) experiments using off‐resonance irradiation have been performed with an agar gel model by systematically varying offset frequency, amplitude of the RF irradiation and gel concentration. The experimental results are shown to be quantitatively modelled by a two‐pool system consisting of a liquid pool with a Lorentzian line shape and a small semisolid pool with a Gaussian lineshape. The fitted model yields physically realistic fundamental parameters with a T~2~ of the semisolid pool of 13 μs. Further analysis shows that the off‐resonance irradiation MTC experiment has significant limitations in its ability to saturate the semisolid pool without directly affecting the liquid component.

📜 SIMILAR VOLUMES

Quantitative Interpretation of Magnetiza
Quantitative Interpretation of Magnetization Transfer in Spoiled Gradient Echo MRI Sequences
✍ John G Sled; G.Bruce Pike 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 257 KB

A method for analyzing general pulsed magnetization transfer (MT) experiments in which off-resonance saturation pulses are interleaved with on-resonance excitation pulses is presented. We apply this method to develop a steady-state signal equation for MTweighted spoiled gradient echo sequences and c

Nonbalanced SSFP-based quantitative magn
Nonbalanced SSFP-based quantitative magnetization transfer imaging
✍ Monika Gloor; Klaus Scheffler; Oliver Bieri 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 642 KB

## Abstract The previously reported concept for quantitative magnetization transfer (MT) imaging using balanced steady‐state free precession (SSFP) is applied to nonbalanced SSFP sequences. This offers the possibility to derive quantitative MT parameters of targets with high‐susceptibility variatio

Quantitative magnetization transfer imag
Quantitative magnetization transfer imaging using balanced SSFP
✍ M. Gloor; K. Scheffler; O. Bieri 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 889 KB

## Abstract It is generally accepted that signal formation in balanced steady‐state free precession (bSSFP) is a simple function of relaxation times and flip angle only. This can be confirmed for fluids, but for more complex substances, magnetization transfer (MT) can lead to a considerable loss of

Quantitative magnetization transfer stud
Quantitative magnetization transfer studies of apoptotic cell death
✍ Colleen Bailey; Kimberly L. Desmond; Gregory J. Czarnota; Greg J. Stanisz 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 387 KB

## Abstract Magnetization transfer measurements were performed on samples of acute myeloid leukemia cells at early (36 h postcisplatin treatment) and late (48 h posttreatment) stages of apoptosis. Magnetization transfer ratio was calculated and a two‐pool model was fitted to data at two powers and

Quantitative 1H magnetization transfer i
Quantitative 1H magnetization transfer imaging in vivo
✍ John Eng; Toni L. Ceckler; Robert S. Balaban 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 694 KB

A major factor contributing to proton (1H) spin-lattice relaxation in biological tissues is believed to be magnetization transfer between 1H in free bulk water and 1H restricted motion associated with macromolecules. We have shown recently that saturation transfer is an effective approach for studyi