𝔖 Bobbio Scriptorium
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Quantitative in vivo iontophoretic studies

✍ Scribed by Muh-Hwan Su; V. Srinivasan; Abdel-Halim Ghanem; William I. Higuchi

Book ID
102918941
Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
767 KB
Volume
83
Category
Article
ISSN
0022-3549

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✦ Synopsis

An experimental methodology was developed to evaluate the physicochemical basis for in vitro-in vivo correlations in iontophoretic delivery situations. This experimental methodology can be used to quantitatively evaluate the extent of interaction between chemical permeation enhancers and iontophoresis for drug delivery. The inherent advantages of using Ag/AgCl electrodes are fully exploited to control pH and minimize depletion of permeant during prolonged periods of iontophoresis.

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