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Quantitative hypermethylation analysis of the cell cycle regulatory gene, 14-3-3 sigma in gastrointestinal cancer cell lines

✍ Scribed by D. Shibata; F. Sato; J. Yin; Y. Mori; F. Selaru; S. Wang; S. Meltzer

Book ID
110547745
Publisher
Springer
Year
2004
Tongue
English
Weight
238 KB
Volume
11
Category
Article
ISSN
1068-9265

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The tissue inhibitor of metalloproteinase-3 (TIMP-3), a recently cloned member of TIMP gene family, has been implicated in the negative regulation of tumor cell invasion and tumor growth. Down-regulation of this gene has been shown to occur in a mouse carcinogenesis model, suggesting that it might p