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Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer

✍ Scribed by Carmen Jernimo; Henning Usadel; Rui Henrique; Cristina Silva; Jorge Oliveira; Carlos Lopes; David Sidransky


Book ID
117264707
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
216 KB
Volume
60
Category
Article
ISSN
0090-4295

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## Abstract The incidence and mortality of prostate cancer (PC) is approximately 2‐fold higher among African‐Americans as compared to Caucasians and very low in Asian. We hypothesize that inactivation of __GSTP1__ genes through CpG methylation plays a role in the pathogenesis of PC, and its ability