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Quantitative gas chromatographic mass spectrometric determination of pinaverium—bromide in human serum

✍ Scribed by G. A. de Weerdt; R. P. Beke; H. G. Verdievel; F. Barbier; J. A. Jonckheere; A. P. de Leenheer


Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
427 KB
Volume
10
Category
Article
ISSN
1076-5174

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A method has been developed for the blood level determination of the antihypertensive agent tiamenidine hydrochloride. The serum samples are mixed with deuterium labelled tiamenidine hydrochloride as an internal standard and extracted with methylene chloride. The extracts are derivatized with heptaf