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Quantitative Evidence for Persistence of Human Parvovirus B19 DNA in an Immunocompetent Individual

✍ Scribed by P. Cassinotti; G. Siegl

Book ID
106272826
Publisher
Springer
Year
2000
Tongue
English
Weight
49 KB
Volume
19
Category
Article
ISSN
0934-9723

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A nested polymerase chain reaction assay (nPCR) was used to investigate the potential of human parvovirus B19 DNA to persist in blood or bone marrow samples obtained either from blood donors or cadaveric bone donors or from patients presenting with clinical signs of parvovirus B19 infection. The pre

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## Abstract Recent studies have suggested a pathogenic role of human parvovirus B19 (B19) in the development of acute fulminant liver failure in children. The hypothesis was based on the detection of B19 DNA in 8 of 10 explanted livers of children requiring liver transplantation. In the present stu