๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Quantitative diffusion imaging in implanted human breast tumors

โœ Scribed by Cynthia F. Maier; Yael Paran; Peter Bendel; Brian K. Rutt; Hadassa Degani

Book ID
102956124
Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
723 KB
Volume
37
Category
Article
ISSN
0740-3194

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โœฆ Synopsis

Abstract

Quantitative diffusion measurements were performed in tumors arising from inoculation of nude mice with two human breast cancer cell lines (MCF7 and T47D) to evaluate the specificity of this technique for characterizing solid tumors. ADC maps were compared to histology and correlated well with gross tumor morphology. Measured ADCs were highly specific for viable and necrotic tumor in the five T47D tumors included in this study (P < 0.02), while only two of the five MCF7 tumors studied developed distinguishable areas of necrosis. No statistically significant difference was observed in ADCs from viable tumor between the different cell lines (P > 0.05).

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