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Quantitative determination of Zn protoporphyrin IX, heme and protoporphyrin IX in Parma ham by HPLC

✍ Scribed by Jun-ichi Wakamatsu; Hiroko Odagiri; Takanori Nishimura; Akihito Hattori

Book ID: 116737605
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 415 KB
Volume: 82
Category: Article
ISSN: 0309-1740
DOI: 10.1016/j.meatsci.2008.12.011

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## Abstract Heme oxygenase (HO)‐1 is a key player reducing cytotoxicity and enhancing protumoral effects of nitric oxide (NO). We examined zinc protoporphyrin (ZnPP) IX, an HO‐1 inhibitor, to affect tumor growth of LL/2 mouse lung cancer cells. ZnPPIX reduced HO‐1 expression and HO activity in LL/2