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Quantitative determination of vigabatrin and gabapentin in human serum by gas chromatography–mass spectrometry

✍ Scribed by Daniëlle C.R. Borrey; Kristof O. Godderis; Veronique I.L. Engelrelst; Dirk R. Bernard; Michel R. Langlois

Book ID
116350072
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
109 KB
Volume
354
Category
Article
ISSN
0009-8981

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A method has been developed for the blood level determination of the antihypertensive agent tiamenidine hydrochloride. The serum samples are mixed with deuterium labelled tiamenidine hydrochloride as an internal standard and extracted with methylene chloride. The extracts are derivatized with heptaf