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Quantitative Determination of Clavulanic Acid in Plasma by HPLC: Application to a Pharmacokinetic Study

✍ Scribed by Matar, Kamal M.; Nazi, Esmail M.; El‐Sayed, Yousry M.; Al‐Yamani, Mohammed J.; Al‐Suwayeh, Saleh A.; Al‐Khamis, Khalil I.

Book ID
120621649
Publisher
Taylor and Francis Group
Year
2005
Tongue
English
Weight
147 KB
Volume
28
Category
Article
ISSN
1082-6076

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## Abstract A specific, accurate, precise and reproducible high‐performance liquid chromatography (HPLC) method was developed for the estimation of ragaglitazar [(−) DRF 2725, NNC 61‐0029], a novel anti‐diabetic agent, in rat plasma. The assay procedure involved simple liquid/liquid extraction of r