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Quantitative determination of carcinogens and mutagens as alkylating agents following chemical activation

โœ Scribed by M.C. Archer; V.W.S. Eng


Book ID
113136291
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
445 KB
Volume
33
Category
Article
ISSN
0009-2797

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Transforming DNA exposed to either diethyl sulfate (diES) or dimethyl sulfate (diMS) is inactivated. The rate of inactivation depends on the marker tested and on the chemical used: diMS is more active than diES. Cotransformation of linked markers is similarly depressed. In contrast, there is a trans