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Quantitative detection of survivin in malignant pleural effusion for the diagnosis and prognosis of lung cancer

โœ Scribed by Yao-Kuang Wu; Kuei-Tien Chen; Yung-Bin Kuo; Ya-Shu Huang; Err-Cheng Chan

Book ID
116334965
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
214 KB
Volume
273
Category
Article
ISSN
0304-3835

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## Abstract Accumulating evidence implicates epigenetic changes such as hypermethylation in carcinogenesis. We investigated whether DNA methylation of 5 tumor suppressor genes in pleural fluid samples could aid in diagnosis of malignant effusion. In samples from 47 patients with malignant pleural e