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Quantitative CT scan analysis in senile dementia of the Alzheimer type: II. Radioattentuation of grey and white matter

✍ Scribed by Dr. Hans Förstl; Aliatair Burns; Robin Jacoby; Sarah Eagger; Raymond Levy

Book ID
102227572
Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
411 KB
Volume
6
Category
Article
ISSN
0885-6230

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✦ Synopsis

Abstract

The radiodensity of the total intracranial area and of the dorsomedial thalamic nuclei were significantly lower in 60 patients with moderate to severe dementia of the Alzheimer type (DAT) compared to 30 healthy age and sex‐matched controls (p<0.02). The radiodensity of the caudate nuclei was similar in the DAT and the coantrol these effects did not exhibit significant correlations with age, duration of illness or global cognitive impairment. The denstitometric parameters discriminated 78.4% of patients and controls; together with the olanimetric measurements 84.4% of the individuals were classified correctly. A potential contribution of white matter shrinkage to ‘cortical atrophy’ and the possible role of thalamic degeneration in DAT are briefly discussed.

📜 SIMILAR VOLUMES

Quantitative CT scan analysis in senile
Quantitative CT scan analysis in senile dementia of the Alzheimer type: I. Computerized planimetry of cerebrospinal fluid areas
✍ Dr. Hans Förstl; Alistair Burns; Robin Jacoby; Sarah Eagger; Raymond Levy 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 English ⚖ 439 KB

## Abstract Sixty patients with senile dementia of the Alzheimer type (DAT) and 30 age and sex‐matched healthy controls were examined by cranial computed tomography (CT). We undertook this study to evaluate a simple and unbiased quantitative method for the estimation of ventricular and subarachnoid