Prediction of plasma protein binding dis
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Hege Christensen; Mark Baker; Geoffrey T. Tucker; Amin Rostami-Hodjegan
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Article
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2006
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John Wiley and Sons
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English
β 231 KB
π 1 views
Although displacement from plasma protein binding (dPB) is usually of little clinical significance, it should be taken into account when interpreting changes in total plasma concentrations of drugs subject to metabolically based drug-drug interactions (mDDI). The aim of this study was to develop an