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Quantitative change in metabolic fate of drug related to serum protein binding

✍ Scribed by Gerhard Levy


Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
244 KB
Volume
69
Category
Article
ISSN
0022-3549

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Although displacement from plasma protein binding (dPB) is usually of little clinical significance, it should be taken into account when interpreting changes in total plasma concentrations of drugs subject to metabolically based drug-drug interactions (mDDI). The aim of this study was to develop an