## Abstract Quantitative evaluation of brain magnetic resonance imaging (MRI) scans is now an accepted part of the trial of new putative treatments for multiple sclerosis (MS). However, conventional MRI is not pathologically specific, and it does not reveal the details of the pathological processes
Quantitative cerebral magnetic resonance imaging during ACTH treatment of multiple sclerosis
β Scribed by J.P. Armspach; D. Gounot; I.J. Namer; H.H. Ohlenbusch; L. Rumbach; J. Chambron
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 712 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0730-725X
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The adrenocortical function in 52 multiple sclerosis patients was studied and compared to that of ten healthy control subjects. The basic secretion rate of cortisol of the MS patients was within the range of normal. Reactivity of the adrenal cortex to stimulation by synthetic ACTH was markedly reduc
Magnetic resonance scans of 74 patients with multiple sclerosis participating in a controlled trial were compared 6 months before and at the end of a 24-32 months-treatment period with either Cyclosporin A (n = 31) or Azathioprine (n = 43). Both qualitative rating and computation of lesion volume sh
## Abstract Retrospectively, we assessed the specificity of two proposed magnetic resonance imaging (MRI) criteria for multiple sclerosis (MS) in patients suspected to have MS but who ultimately receive another diagnosis. Brain MRIs of 28 patients mixed with 28 MRIs of MS patients from the same coh