Quantitative autofluorescence in the ovine and canine ocular fundus in ceroid-lipofuscinosis (Batten's disease)

Coding sequence and exon/intron organiza

Coding sequence and exon/intron organization of the canine CLN3 (batten disease) gene and its exclusion as the locus for ceroid-lipofuscinosis in english setter dogs

✍ Hisashi Shibuya; Po-Ching Liu; Martin L. Katz; Aristotle N. Siakotos; Dan J. Non 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 358 KB 👁 2 views

Hereditary ceroid-lipofuscinosis in English setters has been proposed to be the canine equivalent of human juvenile ceroid-lipofuscinosis, which results from defects in the CLN3 gene. Analyses were performed to determine whether the disease in English setters is also the consequence of a CLN3 gene m