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Quantitative assessment of water pools by T1ρ and T2ρ MRI in acute cerebral ischemia of the rat

✍ Scribed by Jokivarsi, Kimmo T; Niskanen, Juha-Pekka; Michaeli, Shalom; Gröhn, Heidi I; Garwood, Michael; Kauppinen, Risto A; Gröhn, Olli H

Book ID
109870977
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
344 KB
Volume
29
Category
Article
ISSN
0271-678X

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## Abstract The ability of on‐resonance __T__~1ρ~ (__T__~1ρ~) and off‐resonance __T__~1ρ~ (__T__) measurements to indicate acute cerebral ischemia in a rat model of transient middle cerebral artery (MCA) occlusion was investigated at 4.7 T. __T__~1ρ~ was determined with __B__~1~ fields of 0.4, 0.8,

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## Abstract The NMR relaxation times (__T__~1ρ~, __T__~2~, and __T__~1~) of water, N‐acetylaspartate (NAA), creatine (Cr), choline‐containing compounds (Cho), and lactate (Lac) were quantified in rat brain at 4.7 T. In control animals, the cerebral __T__~1ρ~ figures, as determined with a spin‐lock