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Quantitative assay of 2-acetylaminofluorene and 4-acetylaminofluorene DNA adducts in two mammalian cell lines

✍ Scribed by A.J. Smith; S.E. Willington; R.D. Combes


Book ID
113252648
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
85 KB
Volume
271
Category
Article
ISSN
0165-1161

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✍ Dr. Ofelia A. Olivero; Cristina Semino; Miriam C. Poirier πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 822 KB

DNA adduct induction by N-acetoxy-N-2-acetylaminofluorene (N-Ac-AAF) has been investigated in Chinese hamster ovary (CHO) cells using immunoelectron microscopy. The major RNA and DNA adducts, N-(guanosin-8-yl)-2-aminofluorene (G-C8-AF) and N-(deoxyguanosin-8-yI)-2-aminofluorene (dG-C8-AF), were loca