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Quantitative aspects of metal ion binding to certain transfer RNA anticodon loop modified nucleosides

โœ Scribed by SCHWEIZER, M; DE, N; PULSIPHER, M; BROWN, M; REDDY, P; PETRIEIII, C; CHHEDA, G

Book ID
121776962
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
733 KB
Volume
802
Category
Article
ISSN
0304-4165

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Biologically active DNA analogs of tRNA Phe (tDNA phi) were used to investigate metal ion interaction with tRNA-like structures lacking the 2'OH. Binding of Mg 2 ยง to the 76 oligonucleotide tDNA ehe, monitored by circular dichroism spectroscopy, increased base stacking and thus the conformational st