Quantitative analysis of plasminogen activator in small arteries by modified fibrin plates

✍ Scribed by Gary R. Jacobs; John F. Reinisch; Dr. Charles L. Puckett

• Book ID: 102511527
• Publisher: John Wiley and Sons
• Year: 1982
• Tongue: English
• Weight: 326 KB
• Volume: 3
• Category: Article
• ISSN: 0738-1085
• DOI: 10.1002/micr.1920030304

✦ Synopsis

Abstract

The assay of plasminogen activator at the intimal surfaces of arteries less than 2 mm in diameter is possible using streptokinase‐ treated fibrin plates. Femoral arteries obtained from rats showed a reproducible fibrinolysis at their intimal surfaces that could be quantitated for the analysis of plasminogen activator. Utilization of the assay adjusted to the experimental situation would give a method of evaluating changes in the concentration of plasminogen activator at the intimal surface of small arteries when studied under various research conditions.