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Quantitative Analysis of Howell-Jolly Bodies in Children with Sickle Cell Disease

โœ Scribed by Virginia L. Harrod; Thad A. Howard; Sherri A. Zimmerman; Stephen D. Dertinger; Russell E. Ware


Book ID
113616255
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
141 KB
Volume
35
Category
Article
ISSN
0301-472X

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Variation in the level of fetal hemoglobin (HbF) accounts for much of the clinical heterogeneity observed in patients with sickle cell disease (SCD). The HbF level has emerged as an important prognostic factor in both sickle cell pain and mortality, and a % HbF of 10-20% has been suggested as a thre