𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Quantitative Analysis of HIV-1 Protease Inhibitors in Cell Lysates Using MALDI-FTICR Mass Spectrometry

✍ Scribed by van Kampen, Jeroen J. A.; Burgers, Peter C.; de Groot, Ronald; Osterhaus, Albert D. M. E.; Reedijk, Mariska L.; Verschuren, Esther J.; Gruters, Rob A.; Luider, Theo M.

Book ID
120646400
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
140 KB
Volume
80
Category
Article
ISSN
0003-2700

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Quantitative analysis of 5α-reductase in
Quantitative analysis of 5α-reductase inhibitors in DU145 cells using matrix-assisted laser desorption/ ionization time-of-flight mass spectrometry and high-performance liquid chromatography/tandem mass spectrometry
✍ Min-Jung Kang; Sonal Mathur; Rolf W. Hartmann 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB 👁 1 views

## Abstract __N__‐(Dicyclohexyl)acetylpiperidine‐4‐benzylidene‐4‐carboxylic acid (**1**) is an excellent __in vitro__ inhibitor of 5α‐reductase (5αR). Compound **1** showed, however, much lower inhibition activity of 5αR __in vivo__ than __in vitro__, which might be caused by poor membrane permeabi