Quantitative analysis of 6-hydroxymelato
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Masahiro Tetsuo; Sanford P. Markey; Robert W. Colburn; Irwin J. Kopin
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Article
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1981
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Elsevier Science
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English
β 653 KB
A method for assay of urinary dhydroxymelatonin, the major metabolite of the pineal hormone melatonin is described. After addition of an internal standard of deuterated 6hydroxymelatonin sulfate, human mine was hydrolyzed enzymatically and free dhydroxymelatonin extracted, reacted to form a stable t