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Quantitative analysis of benzo[a]pyrene biotransformation and adduct formation in Ahr knockout mice

✍ Scribed by Carlos Sagredo; Steinar Øvrebø; Aage Haugen; Yoshiaki Fujii-Kuriyama; Rita Bæra; Ingrid V. Botnen; Steen Mollerup

Book ID
119379067
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
707 KB
Volume
167
Category
Article
ISSN
0378-4274

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In vivo formation of benzo (a) pyrene di
In vivo formation of benzo (a) pyrene diol epoxide-deoxyadenosine adducts in the skin of mice susceptible to benzo (a) pyrene-induced carcinogenesis
✍ Stephen W. Ashurst; Gerald M. Cohen 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 French ⚖ 824 KB

## Abstract The hydrocarbon‐deoxyribonucleoside adducts formed in mouse skin DNA have been determined following topical application of an initiating dose of benzo(a)pyrene to Swiss mice, a strain shown to be susceptible to benzo(a)pyrene‐induced skin carcinogenesis. Several DNA‐bound products were