Quantitative analysis of associations between birth defects and suspected human teratogens
β Scribed by Khoury, Muin J. ;James, Levy M. ;Lynberg, Michele C.
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 656 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Contemporary information on the trends and patterns of mortality associated with birth defects and genetic diseases is lacking in the United States. To study these trends and patterns, we used the Multiple-Cause Mortality Files of the National Center for Health Statistics. From 1979 through 1992, 32
TP53 accumulation in human primary breast carcinomas was studied by a quantitative luminometric immunoassay (LIA), and TP53 gene alterations, exons 5-8, were examined by singlestrand conformation polymorphism (SSCP) analysis. In 48 of 142 breast tumor samples, a TP53 gene alteration was identified.