Quantitative analysis and purity evaluation of medroxyprogesterone acetate by HPLC

✍ Scribed by G. Cavina; L. Valvo; R. Alimenti

• Book ID: 103910735
• Publisher: Elsevier Science
• Year: 1985
• Tongue: English
• Weight: 575 KB
• Volume: 3
• Category: Article
• ISSN: 0731-7085
• DOI: 10.1016/0731-7085(85)80071-6

✦ Synopsis

A reversed-phase high-performance liquid chromatographic method was developed for the assay of medroxyprogesterone acetate and for the detection and determination of related steroids present as impurities in the drug. The method was compared with the normal-phase technique of the USP XX and was also applied to the analysis of tablets and injectable suspensions.