Quantitative analysis of SMN1 and SMN2 g
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Yi-Ning Su; Chia-Cheng Hung; Hung Li; Chien-Nan Lee; Wen-Fang Cheng; Po-Nien Tsa
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Article
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2005
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John Wiley and Sons
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English
⚖ 244 KB
## Communicated by Graham R. Taylor Autosomal recessive spinal muscular atrophy (SMA) is a common, fatal neuromuscular disease caused by homozygous absence of the SMN1 gene in approximately 94% of patients. However, a highly homologous SMN2 gene exists in the same chromosome interval, centromeric